《Table 1–Formulations of tablets (mg) .》
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《Formulation design of granules prepared by wet granulation method using a multi-functional single-punch tablet press to avoid tableting failures》
Each 240 mg tablet contained 60 mg of API-A，along with anhydrous lactose and granulated lactose as vehicles，CPD as a disintegrant，PVP as a binder，polysorbate 80 as a solubilizing agent，and MgSt as a lubricant in the quantities shown in Table 1.First，API-A，anhydrous lactose，granulated lactose，and CPD（1）were mixed in a fluidized bed granulator.The flowing powder mixture was sprayed with a solution of PVP and polysorbate 80 and granulated in the fluidized bed granulator.The granules were dried and passed through a 22-mesh screen.They were then mixed with CPD（2）and MgSt in a rotary mixer to prepare the sample granules.
| 图表编号 | XD00593000 严禁用于非法目的 |
|---|---|
| 绘制时间 | 2018.03.01 |
| 作者 | Takashi Osamura、Yoshiko Takeuchi、Risako Onodera、Masahiro Kitamura、Yoshiteru Takahashi、Kohei Tahara、Hirofumi Takeuchi |
| 绘制单位 | Laboratory of Pharmaceutical Engineering, Gifu Pharmaceutical University、Pharmaceutical Technology Department, Sawai Pharmaceutical Co.Ltd、Laboratory of Pharmaceutical Engineering, Gifu Pharmaceutical University、Laboratory of Pharmaceutical Engineering, G |
| 更多格式 | 高清、无水印（增值服务） |
