《Table 1–Representative ROS-sensitive linkers and their oxidation products.》
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《ROS-responsive drug delivery systems for biomedical applications》
Thioether-containing polymers are one type of the most popular ROS-sensitive materials investigated in biomedical research[47,48].In the presence of oxidative conditions,thioethercontaining polymers undergo phase transition from hydrophobic sulfide to more hydrophilic sulfoxide or sulfone(Table 1).Early in 2004,Hubbell’s group developed the ABA block polymers consisting of poly(ethylene glycol)(PEG) and poly-(propylene sulfide)(PPS) for the design of ROS-responsive polymeric vesicles[22].After treating with H2O2,the DDSs released its payloads due to the destabilization caused by phase transition.
图表编号 | XD00592900 严禁用于非法目的 |
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绘制时间 | 2018.03.01 |
作者 | Wenhui Tao、Zhonggui He |
绘制单位 | Wuya College of Innovation, Shenyang Pharmaceutical University、Wuya College of Innovation, Shenyang Pharmaceutical University |
更多格式 | 高清、无水印(增值服务) |