《Table 3–Physicochemical characterization of Liposomes.》

《Table 3–Physicochemical characterization of Liposomes.》   提示:宽带有限、当前游客访问压缩模式
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《Pulmonary delivery of liposomal dry powder inhaler formulation for effective treatment of idiopathic pulmonary fibrosis》


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aMean±SD(n=3).

The particle size of Liposomal DPI formulation(M2)found to be 0.755±1.2μm,which would be beneficial for deep lung de-position by the process of diffusion(Brownian motion).Batch B2(97.8±0.5%),C2(97.9±0.8%)and M2(98.6±1.0%)showed highest PDR compared to all other prepared formulations(Table 4).Batch B2,C2 and M2 showed the angle of repose in the range 30-350.Batches prepared with Mannitol as cryoprotectant showed the least moisture(2.8±0.4%)in comparison with batches prepared with Lactose and Sucrose.Mannitol was found to be effective in maintaining the size of liposomal vesicles.All the samples were within the limits as per USPXXVII and passes the content uniformity test.