《Table 3–“Tableting properties”of formulations with different amounts of binder, evaluated using ben
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《Formulation design of granules prepared by wet granulation method using a multi-functional single-punch tablet press to avoid tableting failures》
We examined the effect of binder on TFS in formulations with14.4 mg of disintegrant per tablet.Each tablet contained PVP at 4 mg in Sample 4，8 mg in Sample 5，12 mg in Sample 1，18 mg in Sample 6，or 24 mg in Sample 7（Table 1）.TFS was<2 MPa in Samples 4 and 5，and the points were plotted in range（IV），indicating poor“Compactability”（Table 3；Fig.3）.Therefore，≥12 mg of binder is needed to give sufficient hardness（Table 3；Fig.3）.
| 图表编号 | XD00593300 严禁用于非法目的 |
|---|---|
| 绘制时间 | 2018.03.01 |
| 作者 | Takashi Osamura、Yoshiko Takeuchi、Risako Onodera、Masahiro Kitamura、Yoshiteru Takahashi、Kohei Tahara、Hirofumi Takeuchi |
| 绘制单位 | Laboratory of Pharmaceutical Engineering, Gifu Pharmaceutical University、Pharmaceutical Technology Department, Sawai Pharmaceutical Co.Ltd、Laboratory of Pharmaceutical Engineering, Gifu Pharmaceutical University、Laboratory of Pharmaceutical Engineering, G |
| 更多格式 | 高清、无水印（增值服务） |
