《Table 4Pharmacokinetic parameters of salidroside a singly, or multiply intragastric administration

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《Salidroside shows a particular pharmacokinetic property in model rats of myocardial ischemia》

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#P<0.01 vs single administration of control group；*P<0.01 vs multiple administration of control group.

The inter-batch and intra-batch accuracy for salidroside at the four levels of 1，2，100，and 4000 ng/m L（n=5）were presented as the percentage of error，which were examined based on the ratio of the mean measured value to the mean marked value.However，the inter-batch and intra-batch precision were estimated by examining the RSD%at the same four concentrations as the accuracy.The inter-day and intra-day precision in rat plasma samples were no more than 8.8%for every concentration，and the accuracy was over a range of-3.8%–4.6%.Entire values of RE%as well as RSD%are listed in Table 1，which totally accord with the standards formulated from the guidance Bioanalytical Method Validation of FDA（2015）.