《Table 1.Structures and Activities of TNAP Inhibitors》

《Table 1.Structures and Activities of TNAP Inhibitors》   提示:宽带有限、当前游客访问压缩模式
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《3D-QSAR and Surflex Docking Studies of a Series of Alkaline Phosphatase Inhibitors》


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01~10,22~30,38~40 R1=4-methylphenyl;11~17,31~35 R1=phenyl;18~20,36 R1=butyl;21 and 37 R1=pentyl;01~21,38,39 R2=NO2;22~37 R2=NH2;40 R2=Br;01~39 R3=H;40 R3=Br

The structure and activity data of TNAP inhibitors used in this study were collected from the literature by Mariia Miliutina et al.IC50 was converted to p IC50 by taking–Log IC50.The structures and activities(p IC50)used for QSAR analysis are given in Table 1.