《Table 2 Sources of flavonoid compounds and their antiviral activities》

  提示：宽带有限、当前游客访问压缩模式

本系列图表出处文件名：随高清版一同展现

《Role of flavonoids in plant interactions with the environment and against human pathogens-A review》

1. 获取 高清版本忘记账户？点击这里登录

1. 下载图表忘记账户？点击这里登录

The inhibitory activity of flavonoids against human immunodeficiency virus（HIV）is the most important and dynamic area of research in plant sciences.Most of the research work has focused against pandemic HIV-1strain and its enzyme profiles.Flavonoid（Baicalein）has shown pronounced inhibitory activity to HIV-1 infection and replication of many other viruses（Tripoli et al.2007；González-Molina et al.2010）.Flavonoids with glycone exhibit more inhibitory activity to rotavirus than those with aglycone form（Bae et al.2000）.Because of several catechins，robustaflavone and hinokiflavone have also possessed activity against HIV-1 reverse transcriptase.Though catechins typically inhibit DNA polymerases，their interaction with the HIV-1 enzyme is not specific in nature（Moore and Pizza 1992；Hisayoshi et al.2015）.Moreover，several flavonoids like 3，2′-dihydroxyflavone and demethylated gardenin A inhibit the activity of HIV-1 proteinase（Brinkworth et al.1992），whereas quercetagetin，myricetin，quercetin 3-O-（2′′-galloyl）-α-L-arabinopyranoside and Robinette inhibit HIV-1 integrase（Kim et al.1998；Vandeputte et al.2010；Pasetto et al.2014）.Previously，two research groups proposed a well understanding inhibitory action of mechanisms for HIV-1 enzymes（Fesen et al.1994；Righi et al.2017）.Interestingly，flavonoids have also shown inhibitory potential against the respiratory syncytial virus，herpes simplex virus，poliovirus，parainfluenza virus，adenovirus，and Sindbis virus（Kaul et al.1985；Kim et al.1998；Pasetto et al.2014）.The galangin flavonoids display antiviral activity against Coxsackie B virus as well as HSV（Meyer et al.1997）.Like antibacterial，synergism between flavonoids and other antiviral agents has also been documented（Mucsi et al.1992）.Antiviral properties of different classes of flavonoids are summarized in Table 2.