《Table 2.Cytotoxic activities and molecular mechanisms of morusin against different human cancer cel

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《Phenolic constituents from the root bark of Morus alba with emphasis on morusin and its anti-cancer properties》

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Abbreviations:Bax=Bcl2-associated X protein，CCAAT-enhancer binding proteinβ（C/EBPβ），COX-2=cyclooxygenase-2，DR5=death receptor 5，EGFR=epidermal growth factor receptor，3-MA=3-methyladenine，MAPK=mitogen-activated protein kinase，NF-κB=nuclear facto

Major classes of phenolic compounds isolated from the root bark of M.alba are flavonoids and benzofurans（Table 1）.They represent 48%and 38%of the phenolic constituents，respectively（Fig.2）.Other compounds are those of stilbenoids（7%），triterpenes（5%），phenolic acids（1%）and coumarins（1%）.