《Table 1.Triptolide Modulates Autophagy in vitro》

《Table 1.Triptolide Modulates Autophagy in vitro》   提示:宽带有限、当前游客访问压缩模式
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《"Triptolide, A Potential Autophagy Modulator"》


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Notes:↑:increase;↓:decrease;LC3:microtubule-associated protein 1 light chain 3;ERK:extracellular regulated protein kinase;ER:endoplasmic reticulum;ATG:autophagy-related gene;mTORC1:mammalian target of rapamycin complex 1;ULK:unc-51-like kinase;PI3KⅢ:pho

Up-to-date,it is demonstrated that triptolide functions in neuroprotecion,anti-tumorigenic effects through autophagic pathways in in vitro and in vivo models.Autophagy also involves in hepatotoxicity and cardiotoxicity of triptolide.Moreover,triptolide can protect podocyte via modulation of autophagy.As described in more detail in Tables 1 and 2,we list the studies supporting triptolide as an autophagy modulator.