《Table 2.Triptolide Modulates Autophagy in vivo》

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《"Triptolide, A Potential Autophagy Modulator"》

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Notes:↑:increase；↓:decrease；LC3:microtubule-associated protein 1 light chain 3；m TOR:mammalian target of rapamycin

Up-to-date，it is demonstrated that triptolide functions in neuroprotecion，anti-tumorigenic effects through autophagic pathways in in vitro and in vivo models.Autophagy also involves in hepatotoxicity and cardiotoxicity of triptolide.Moreover，triptolide can protect podocyte via modulation of autophagy.As described in more detail in Tables 1 and 2，we list the studies supporting triptolide as an autophagy modulator.