《Table 4 Stability of peptide-HLA-A*0201 complexes》
提示:宽带有限、当前游客访问压缩模式
本系列图表出处文件名:随高清版一同展现
《A modified HLA-A~*0201-restricted CTL epitope from human oncoprotein (hPEBP4) induces more efficient antitumor responses》
Results are expressed as the MFI,defined as 100%at 0 h;the MFI from other time points are relative to 0 h.Data are presented as the mean±s.e.m.of six independent experiments.Abbreviation:MFI,mean fluorescence intensity.
The immunogenicity of MHC class I-restricted peptides requires the capacity to bind and stabilize MHC class I molecules on the cell surface.Therefore,we next sought to measure directly the interaction strength between the peptides and HLA-A2.1 using a conventional binding and stabilization assay with T2 cells.Of the 17 peptide analogs,16(except 7H)had stronger affinity than the native peptide P40–48(Table 3).
图表编号 | XD0010736000 严禁用于非法目的 |
---|---|
绘制时间 | 2018.08.01 |
作者 | Weihong Sun、Junyi Shi、Jian Wu、Junchu Zhang、Huabiao Chen、Yuanyuan Li、Shuxun Liu、Yanfeng Wu、Zhigang Tian、Xuetao Cao、Nan Li |
绘制单位 | National Key Laboratory of Medical Immunology and Institute of Immunology,Second Military Medical University、Institute of Immunology,Zhejiang University School of Medicine、Biotherapy Center,The Affiliated Central Hospital of Qingdao University、Department |
更多格式 | 高清、无水印(增值服务) |
查看“Table 4 Stability of peptide-HLA-A*0201 complexes”的人还看了
- Table 2 Results of the storage stability of imidacloprid residues in 4 dif-ferent matrixes of L.barbarum