《Table 1–Apparent stability constant (Ks) of CA inclusion complexes.》

《Table 1–Apparent stability constant (Ks) of CA inclusion complexes.》   提示:宽带有限、当前游客访问压缩模式
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《Effect of antioxidant activity of caffeic acid with cyclodextrins using ground mixture method》


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Phase solubility studies were conducted to assess the molar ratio of the CA/CD inclusion complexes and their stability constants in an aqueous solution.Results of the solubility testing indicated that the solubility of CA increased linearly forαCD andβCD,producing an ALtype of phase solubility diagram according to the classification system of Higuchi and Connors[19],(Fig.2) .Typically,an ALdiagram indicates that a complex is formed at a molar ratio of 1/1[20],so both CA/αCD and CA/βCD formed a complex at a molar ratio of 1/1 in solution.The stability constant(Ks)was determined next.Ks was 1547.5 M-1forαCD and 371.4 M-1forβCD(Table 1).A study by Iacovino et al.reported that,when a complex has a stability constant exceeding 1000 M-1,the guest molecule and CD are unlikely to dissociate[21].CA included inαCD had a stability constant of1547.5 M-1,so CA was more stable inside the cavity ofαCD than it was inside the cavity ofβCD.