《Table 1 Upregulated and downregulated genes in Schwann cells by microarray analysis》

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《Comparative study of microarray and experimental data on Schwann cells in peripheral nerve degeneration and regeneration: big data analysis》

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RT-PCR:Reverse transcription-polymerase chain reaction；qPCR:quantitative polymerase chain reaction；ChIP:chromatin immunoprecipitation；WB:western blotting；IHC immunohistochemistry；mRNA:messenger ribonucleic acid；ISH:in situ hybridization.

This study，which is part of a big data analysis，was conducted under the assumption that knowledge of different types of genes and their characteristics and functions（i.e.，whether they are up-or downregulated）will allow for the easy detection of genes that are appropriate for experimental studies on Schwann cells.Additionally，some genes may act differently under different experimental conditions.This method could be a helpful and effective way to detect gene expression in future experimental studies.In conclusion，some genes are highly expressed in microarray studies but weakly expressed in experimental studies.Therefore，a microarray may not be a good tool for Schwann cell studies because the genes may be differently expressed.Conversely，some genes are weakly expressed in microarray studies and highly expressed in experimental studies；these genes are more promising targets for examination in future Schwann cell studies（Table 1）.Therefore，microarray analysis could be a good tool for Schwann cell studies.