《Table 1 Atoh1 expression and its function in cell types other than hair cells》

《Table 1 Atoh1 expression and its function in cell types other than hair cells》   提示:宽带有限、当前游客访问压缩模式
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《Atoh1转录因子在耳蜗内的转译后调节(英文)》


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In addition to hair cell formation,Atoh1 plays important roles in the differentiation and formation of several other cell types.Atoh1 knockout induces cell loss in several tissues,including cerebellar granule cells(Ben-Arie et al.,1997;Flora et al.,2007;Forget et al.,2014),retrotrapezoid nucleus(RTN)neurons in the medulla(Wang et al.,2005;Huang et al.,2012;Ruffault et al.,2015),dorsal commissural interneurons in the spine(Miesegaes et al.,2009),intestinal goblet cells(Yang et al.,2001;Van Dussen and Samuelson,2010),and Merkel cells in the skin(Ben-Arie et al.,2000;Fr?hlich et al.,2009;Morrison et al.,2009;Maksimovic et al.,2014;Wright et al.,2015).The distribution of Atoh1 in cells other than inner ear hair cells and the associated phenotypes in loss-of-function assays are listed in Table 1.