《Table 5 Associations between rs17042171 genotypes and AF analyzed by multivariable logistic regress
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《中国中原地区汉族人群染色体4q25上rs17042171与心房颤动有关(英文)》
*The value after adjusting for age,LAD,CAD,and HP
The genoty pe frequencies of 5 SNPs in all the subjects were successfully genotyped and did not deviate from Hardy-Weinberg equilibrium both in the AF and control groups(P>0.05,Table 3).The correlations between rs17042171 and AF based on the 4 standard genetic models(co-dominant,dominant,recessive,and additive)were listed in Table 4,where the recessive model had a minimum P value(0.002).Using multivariate logistic regression models(adjusting factors including age,LAD,CAD,and HP),we observed that patients with the AA genotype were still of the minimum P value,even if which was corrected by the Bonferroni method,compared with those with non-AA in the recessive model(OR:5.591,95%CI 2.176 to 14.365,P-B<0.008;Table 5).There was no evidence of associations between the other 4 SNPs and AF(data not shown).
图表编号 | XD0026941900 严禁用于非法目的 |
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绘制时间 | 2018.06.01 |
作者 | 王旭、聂亚莉、宁姝威、师勇、赵育洁、牛思泉、郭成贤、孟祥光、袁义强 |
绘制单位 | 南方医科大学附属河南心血管病医院心内科、郑州大学基础医学院药理学教研室、郑州市第七人民医院心血管疾病及药物研究室、郑州市第七人民医院泌尿外科、郑州市第七人民医院心内科、郑州市第七人民医院心内科、中南大学湘雅三医院临床药理研究中心、郑州市第七人民医院心血管疾病及药物研究室、南方医科大学附属河南心血管病医院心内科 |
更多格式 | 高清、无水印(增值服务) |
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