《Table 5 Adverse events during the study treatment》

《Table 5 Adverse events during the study treatment》   提示:宽带有限、当前游客访问压缩模式
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《定心方联合胺碘酮治疗室性早搏:一项随机、双盲、多中心、安慰剂对照试验(英文)》


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Note:*P<0.05 was considered statistically significant.

Over 98%of patients in three groups rated the overall tolerability of the three treatments as―good‖or―very good‖.Thirty-six adverse events occurred in 10 participants given amiodarone combined with DXR placebo(13 events),9participants given DXR combined with amiodarone placebo(13 events)and 7 participants given DXR combined with amiodarone(10 events),consisting of 10 cases of rash(4 in the amiodarone group,3 in the DXR group and 3 in the DCA group),9 cases of nausea(3 in the amiodarone group,4 in the DXR group and 2 in the DCA group),7 cases of abdominal pain(3 in the amiodarone group,2 in the DXR group and 2 in the DCA group).Among those,4 events were classified as possibly related to drug.No drug-related serious adverse events occurred during the study treatment,and no statistical difference was observed among the three groups for all adverse events.With regard to laboratory parameters for safety,there were no clinically relevant changes in the three groups(Table 5).