《表6 中心组合设计的试验结果和预测值》

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《响应面法优化阿维链霉菌生产多拉菌素的培养基（英文）》

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Fig.1～3 showed the response surface plots for the present study and illustrated the pair-wise interaction of the three variables.The predicted maximum doramectin production（101.29mg/mL）derived from RSM regression was obtained when the concentration of 18g/L dry yeast，0.16g/L MgSO4 and 0.09g/L NH4Cl，respectively.Doramectin production in the optimized media was103.54g/mL（the average value of three replications），and the production increased 1.80 times compared with that using the original medium（36.93g/mL）.