《Table 2 Clinical course of six pregnant patients with hyperthyroid heart disease》

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《Hyperthyroid heart disease in pregnancy: Retrospective analysis of a case series and review of the literature》

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During the 5-year study period，69389 women delivered at our hospital.A total of 155patients were diagnosed with hyperthyroidism，and six patients were diagnosed with HHD，with the New York Heart Association classification of cardiac function ranging from III to IV.Two of the patients with HHD were further complicated with acute heart failure attacks.Both of these two patients had been previously diagnosed with GD but used ATDs irregularly without thyroid function monitoring or preconception counselling.Only three patients had regular antenatal care.Another patient never had antenatal care during pregnancy.Thyroid function tests revealed that the total thyroxine（T4）and triiodothyronine（T3）levels ranged from 176.8 nmol/L to 390.0nmol/L and 2.99 nmol/L to 7.67 nmol/L，respectively.The plasma levels of thyroid globulin antibody（TGAb）and thyroid peroxidase antibody（TPOAb）were very high in these six patients.The follow-up of these patients showed good outcomes.Tables 1and 2 present the clinical features of the six patients.