《Table 1Clinical characteristics of study patients with COVID-19.》

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《感染新型冠状病毒的2型糖尿病患者的临床特征和结果——一项回顾性研究》

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The present study showed significant differences in comorbidities for diabetic COVID-19 patients versus non-diabetic patients，including hypertension（58.3%vs 31.3%，P<0.001)，coronary heart disease （17.7%vs 8.0%，P=0.035），and chronic renal disease （6.3%vs 0%，P=0.007）.It has been well established that hypertension，coronary heart disease，and chronic renal disease coexist with diabetes，leading to a higher risk of morbidity and mortality for COVID-19.In diabetic patients and patients with related glucose and lipid dysfunctions，the angiotensin-converting enzyme 2(ACE2）receptor overexpresses in multiple organs such as the lung，kidney，and liver，which facilitates the receptor-binding domain of the spike protein of SARS-Co V-2 bound to the cell receptor ACE2[19].Several lines of evidence suggest that diabetes is a risk factor for the progression and prognosis of COVID-19[17，20].Our study enhanced this hypothesis.Nonetheless，the prevalence of cerebrovascular disease，hepatitis B infection，cancer，and chronic obstructive pulmonary disease（COPD）history was comparable between the two groups.