《Table 1 Novel three-finger toxin biological effects and their potential applications》

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《Last decade update for three-finger toxins: Newly emerging structures and biological activities》

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ASIC:Acid sensing ion channel；GABAA:Type A receptor of gamma-amino butyric acid；FX:Factor X.

This minireview briefly summarizes the data obtained for TFTs during the last decade（Table 1）.The toxins with new structural features appearing in the recent literature are considered herein；those that have garnered the most interest is the covalently-bound TFT dimers.In addition，the recently discovered uncommon biological activities of some TFTs are discussed；these include the so-called mambalgins that exert a potent analgesic effect upon central and peripheral injection and represent the most remarkable discovery of late.