《Table 5 Clinicohistopathological association of nuclear immunoexpressions of Cyclin D1, Slug and Sn

《Table 5 Clinicohistopathological association of nuclear immunoexpressions of Cyclin D1, Slug and Sn   提示:宽带有限、当前游客访问压缩模式
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《Clinicohistopathological implications of phosphoserine 9 glycogen synthase kinase-3β/β-catenin in urinary bladder cancer patients》


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Non parametric Mann Whitney U test was used to determine the P-values;a P values≤0.05 are considered as significant.

Present study was performed on a cohort of 90 patients with UCB and 10 normal tissues.Median age of these patients was 60 years,ranging from minimum of 38 years to maximum of 82 years.Eleven percent(10/90)patients were female.Of total,80%patients(72/90)were examined with gross painless hematuria as the primary clinical symptom.Smoking/tobacco chewing history of 76 patients was available;out of which 64.5%were regular smokers or tobacco chewers and 35.5%were non-smokers.Fifty three percent(48/90;stage pTa-pT1)patients were presented with non-muscle invasive disease,while 46.7%patients(42/90;stage pT2-pT4)were diagnosed with muscle invasive disease.Histologically,34.4%tumors were classified as low grade carcinomas and 65.6%patients were presented with high grade carcinomas.Among the total 90 patients,43.3%(39/90)patients were diagnosed with the tumor of recurrent type.As per clinicohistopathological records,only 6.7%patients were examined with lymph node metastasis that developed over a mean period of 42 mo since initial diagnosis.Follow up data was available in 71 patients.Of 71 patients,69%patients survived and 28.2%patients showed progression over an average time line of36 mo.Clinicohistopathological profiles of the patients included in the study are summarized in Table 1.