《Table 2 Association of aberrant expression of pS9GSK-3βprotein with clinicohistopathological factor

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《Clinicohistopathological implications of phosphoserine 9 glycogen synthase kinase-3β/β-catenin in urinary bladder cancer patients》

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Non parametric Mann Whitney U test was used to determine the P-values.a P values≤0.05 are considered as significant.N/C expression:Nuclear/cytoplasmic expression.

Out of the total 90 tumors examined，28（31.1%）tumors co-expressed altered protein levels of pS9GSK-3βandβ–Catenin proteins（Figure 2C）.These proteins were observed to be aberrantly co-expressed in 67.9%（19/28）muscle invasive tumors（P=0.01；Mann Whitney U test）；78.6%（22/28）high grade tumors；60.7%（17/28）recurrent tumors（P=0.02；Mann Whitney test）；60.7%（17/28）frequent smokers/tobacco chewers and 82.1%（23/28）tumors from hematuric patients（P=0.04；Mann Whitney U test）（Table 3） .