《Table 5–The zeta potentials of NK (1 0 kIU/ml;pH 5.0) , TUDCA (TUDCA:1 0 mg/ml;p H 5.0) and NK-TUDC

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《Preparation and toxicity evaluation of a novel nattokinase-tauroursodeoxycholate complex》

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The zeta potential of the solutions of NK（10 kIU/ml），TUDCA（10 mg/ml），and NK-TUDCA（NK:10 k IU/ml，TUDCA:10 mg/ml；p H 5.0）were estimated and the results are shown in Table 5.The mean zeta potentials of the solutions of NK，TUDCA，and NK-TUDCA were 2.11±0.30 mV，-6.45±0.74 mV，and-0.94±0.88 mV，respectively.It was found that the positive charge of NK could be covered by the conjugation with the negative charged TUDCA micelles，and the absolute value of TUDCA solutions were also decreased by the electrostatic binding of NK.