《Table 5 Production of cytokines and chemotactic factor in jejunal mucosa of suckling piglets》

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《口服鼠李糖乳杆菌GG影响哺乳仔猪肠道屏障功能的研究（英文）》

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The data followed by different capital letters in the same column are very significantly different（P<0.01）.Data are expressed as mean±SD （n=6）

Six sows（Duroc×Landrace×Yorkshire）were participants in this experiment.Four newborn piglets with similar initial weights were selected from each sow’s offspring.The twenty-four newborn piglets were then randomly divided into two groups.Each group had three litters with four pigs per litter（half male and half female）.The basal diet was supplemented with minerals and vitamins to meet or exceed the requirements for pigs（National Research Council，1998）.All pigs were fed ad libitum.The experiment was approved by and performed in accordance with the guidelines of the Zhejiang University Animal Care and Use Committee，Hangzhou，China.Piglets in the control group were orally administered with 2 mL of sterile skim milk，while the treatment group（L.rhamnosus group）received the same volume of sterile skim milk suspended with viable L.rhamnosus（5×108 CFU/mL）by gavage at the 1st，3rd，and 5th days after birth.From Day 12，piglets were provided with free access to water and a supplemented pre-starter feed.Body weights were recorded at the beginning and the weaning day（the 25th day）in this experiment.Diarrhea was observed every day.Composition and nutrient levels in the diets of sows are listed in Tables S1 and S2，respectively.Composition and nutrient levels in the diets of the pre-starter feed were listed in Tables S3and S4，respectively.No antibiotic was added throughout the trial.The schematic flow diagram of the study design can be found in Fig.S1.