《Table 2 Percentage (%) of gastrocnemius muscle wet weight of rats after sciatic nerve transection》下

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《Effect of exogenous spastin combined with polyethylene glycol on sciatic nerve injury》

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*P<0.05，vs.sham group；#P<0.05，vs.suture group，P<0.05，vs.PEG group（one-way analysis of variance followed by Dunnett’s post hoc test）.Data are expressed as the mean±SD（n=30）.Differences were compared among suture (sciatic nerve transection+nerve s

Because a complete myelin sheath was rarely observed and the myelin sheath disintegrated within 1 to 2 weeks after surgery，the myelin sheath thickness could not be accurately measured at later points.Thus，only complete myelin sheaths observed at 4 and 8 weeks after the operation were examined in each group.Table 4 exhibits changes in myelin sheath thickness of each group after 4 and 8 weeks.At 4 to 8 weeks after surgery，myelin sheath thickness gradually increased，with thicknesses in the order of sham group>PEG+spastin group>PEG group>suture group.Myelin sheath thickness was significantly different among sham，suture，PEG，and PEG+spastin groups（P<0.05）.At 8 weeks after surgery，myelin sheath thickness in the PEG+spastin group was similar to that observed in the sham group（P>0.05）.Myelin sheath thickness in the PEG+spastin group was not significantly different at 4 and 8weeks after surgery.However，myelin sheath thickness was significantly different between suture and PEG groups（P<0.05；Table 4）.