《Table 1 Identification of plasma biomarkers in HCMV hepatitis cases》
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《基于UHPLC-MS的代谢组学技术研究婴儿巨细胞病毒肝炎湿热内蕴证(英文)》
Note:aVariable importance in projection(VIP)values were obtained from OPLS-DA models with a threshold of 1;bContent variance compared to normal group.Levels of potential biomarkers were labeled with(↓)down-regulated and(↑)up-regulated.
For plasma samples,664and 412compounds were detected in the positive ion mode for the upper and lower phases.Both unsupervised PCA scores plot(Figure 1A,Figure2A)and supervised OPLS-DA scores plot(Figure 1B,Figure 2B)showed significant differences in the metabolomic profiles between the patients and NCs,demonstrating that the metabolites in plasma were altered by HCMV hepatitis.The R2 Y values for the OPLS-DA model were 0.980for the upper phase and 0.950for the lower phase.Q2 values were 0.869for the upper phase and 0.898for the lower phase.Finally,22differential biomarkers were identified in the plasma samples(Table 1).
图表编号 | XD0038492700 严禁用于非法目的 |
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绘制时间 | 2019.01.15 |
作者 | 李维薇、汪受传、单进军、谢彤、林丽丽、贺丽丽、杜丽娜、杨燕 |
绘制单位 | 南京中医药大学附属医院、南京中医药大学中医儿科学研究所、南京中医药大学附属医院、南京中医药大学中医儿科学研究所、南京中医药大学中医儿科学研究所、南京中医药大学中医儿科学研究所、南京中医药大学附属中西医结合医院、首都医科大学附属北京儿童医院、首都医科大学附属北京儿童医院 |
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