《Table 1Data at entry in patients with DIAIH versus AIH.》

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《CD4~+Foxp3~+CD25~(+/-)Tregs characterize liver tissue specimens of patients suffering from drug-induced autoimmune hepatitis: A clinical-pathological study》

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AIH:autoimmune hepatitis；DIAIH:drug-induced autoimmune hepatitis；EO:eosinophil；ALT:alanine aminotransferase；AST:aspartate aminotransferase；TBil:total bilirubin；ALP:alkaline phosphatase；GGT:gamma-glutamyltransferase；Ig G:immunoglobulin G；PT:prothrombin tim

Clinical characteristics of patients with DIAIH and AIH at initial presentation are summarized in Table 1.All DIAIH patients were female，with a median age of 53.12 years（46.43–57.18）.Total 95.8%（23/24）of AIH patients were female，with a median age of 54.26 years（46.53–65.17）.The median values of ALT and AST were 404.50 U/L（299.00–734.75）and 454.10 U/L（287.00–767.00）in DIAIH patients and 309.50 U/L（158.32–574.75）and 315.00 U/L（177.95–396.33）in AIH patients，respectively.The ALT and AST values were significantly higher in DIAIH than those in AIH patients（P<0.05）.However，there was no significant difference in other biochemical data between the two groups.All DIAIH and AIH patients were positive for ANA.The median values of ANA titres were1:320（1:320–1:1000）in DIAIH and 1:1000（1:320–1:1000）in AIH，respectively，without significant difference between two groups.There were positive for SMA in one of the AIH patients and two of the DIAIH patients.But all patients tested negative for anti-LKM-1as well as SLA/LP antibodies.