《Table 2.Changes in eGFR when 24-h UPE<or≥1.5 g in CKD Patients at Three Periods[mL·min-1·1.73 m-

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《"Effects of Niaoduqing Particles(尿毒清颗粒)on Delaying Progression of Renal Dysfunction:A Post-trial,Open-Label,Follow-up Study"》

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Notes:Because of missing values，the number of participants were not equal in 24-h UPE to total number of FAS.UPE，urinary protein excretion；IQR，interquartile range；eGFR，estimated glomerular filtration rate；P<0.05 vs.placebo group；△P<0.05，△△P<0.01，c

We also analyzed the changes in eGFR in the subgroups relative to baseline eGFR，after grouping according to 24-h UPE<1.5 g or 1.5 g（Table 2）.In the subgroups of 24-h UPE<1.5 g，there was no difference in e GFR at baseline，24 and 48 weeks（P=0.801，0.210and 0.195，respectively）.After 24-week treatment，the median e GFR in the Niaoduqing group were not different from baseline（P=0.485），but decreased in the placebo group（P=0.011）.After 48-week treatment，the median e GFR was not different from baseline in the Niaoduqing group（P=0.645），but decreased significantly from baseline in the placebo group（P<0.001）.At 48 weeks，e GFR changes from baseline was significant different between the two groups（P=0.024）.Although there was no statistical difference in eGFR changes in the two groups between 24 and 48 weeks（P=0.893），e GFR in the placebo group deceased significantly from 24 weeks（P=0.036），and no change in the Niaoduqing group was observed（P=0.087）.