《Table 1 Differential diagnosis of pancreatic cystic lesions》

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《Cyst fluid glucose: An alternative to carcinoembryonic antigen for pancreatic mucinous cysts》

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IPMN:Intraductal papillary mucinous neoplasm；MCN:Mucinous cystic neoplasm；PC:Pseudocyst；SCN:Serous cystic neoplasm；NET:Neuroendocrine tumor；SPN:Solid pseudopapillary neoplasm；MPD:Main pancreatic duct；CEA:Carcinoembryonic antigen.

The accurate diagnosis of PCLs is critical to guarantee the best management for these patients，whether through surgical resection or periodic surveillance[6-8].Unfortunately，there is no a single test accurate enough to assure a definitive diagnosis for all PCLs，particularly for those that are isolated unilocular cystic lesions，with neither perceptible communication with the main pancreatic duct（MPD）nor previous episodes of pancreatitis[9].Therefore，a combination of information obtained from demographics，clinical history and imaging，as well as cytopathology and cyst fluid markers obtained by endoscopic ultrasound-guided fine needle aspiration（EUS-FNA），has been used for the differential diagnosis of PCLs（Table 1）.