《Table 1 Prognostic values of pre-and postoperative levels of carcinoembryonic antigen and carbohydr

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《Prognostic significance of perioperative tumor marker levels in stage Ⅱ/Ⅲ gastric cancer》

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HR:Hazard ratio；CI:Confidence interval；CEA:Carcinoembryonic antigen；CA19-9:Carbohydrate antigen 19-9.

The perioperative characteristics of the 998 patients are summarized in Supplemental Table 1.The median values of preoperative serum CEA and CA19-9 were 2.4 ng/mL and 12.0 IU/mL，respectively，and 192（19.2%）and 162（16.2%）patients had levels of preoperative serum CEA and CA19-9 higher than the cutoff values.Patients were pathologically diagnosed with stages IIA（n=236），IIB（n=222），IIIA（n=297），IIIB（n=174），and IIIC（n=69）.The median values of postoperative serum CEA and CA19-9were 2.2 ng/mL and 8.8 IU/mL，respectively，and 114（11.4%）and 83（8.3%）patients had postoperative serum CEA and CA19-9 levels higher than the cutoff values.Postoperative adjuvant chemotherapy was administered to 646（64.7%）patients.The median postoperative follow-up period was 50.5 months（range 3.5-93.7 mo）.