《Table 1 Demographic data and clinical profile of the recruited patients》

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《冠心病患者白细胞miR-223-3p水平与氯吡格雷治疗后的血小板反应无关（英文）》

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Data of platelet aggregation，age，and BMI are presented as x±s.BMI:Body mass index；PCI:Percutaneous coronary intervention；ACEI:Angiotensin-converting enzyme inhibitor；CCA:Calcium channel antagonist；ARB:Angiotensin receptor blocker

Clinical phenotypes of interest—NR or UR to clopidogrel—were identified by ADP-induced platelet aggregation as measured with electronic impedance values（Figure 1）.Clinical characteristics and clopidogrel responses between NR and UR groups are summarized in Table 1.The impedance values ranged from 0 to 1Ωin the UR group and from 12 to 21Ωin the NR group.UR exhibited significantly lower ADP-induced platelet aggregation than NR（0.7±0.5 vs.15.0±2.5，P<0.001）.However，there were similar distributions in other clinical characteristics between the 2 groups，such as age，gender，BMI，smoking，bleeding events，previous PCI or stroke，diabetes mellitus，dyslipidemia，hy per tension，and concomitant use of other select medications，except for more use of beta blockers in the NR group.