《Table 1 Demographic and clinical characteristics of the subjects》

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《Regional gray matter abnormality in hepatic myelopathy patients after transjugular intrahepatic portosystemic shunt: a voxel-based morphometry study》

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Data are expressed as the mean±SD with the exception of sex，handedness，Child-Pugh stage，and West-Haven HE grade（n）.*:One-way analysis of variance；#:Chi-square test；:nonparametric Kruskal-Wallis H test；$:independent-samples t test.HE:Hepatic encephal

One-way analysis of variance across the hepatic myelopathy，non-hepatic myelopathy，and healthy control groups showed significant differences in gray matter volume in both thalami，putamina，globi pallidi，parahippocampi，and in the cerebellum and vermis（Table 2 and Figure 2）.As compared with the healthy controls，both hepatic myelopathy and non-hepatic myelopathy patients showed increased gray matter volumes in both thalami and parahippocampi，with decreased gray matter volumes in the putamina，globi pallidi，cerebellum，and vermis（Table 3 and Figure 3A&B）.Additionally，compared with the non-hepatic myelopathy group，gray matter volume was increased in the right cau-date nucleus，and decreased in the left insula，left thalamus，left superior frontal gyrus，and middle cingulate cortex in the hepatic myelopathy group（Table 4 and Figure 3C）.