《Table 1 Baseline characteristics of the recruited participants in the cross-sectional study》

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《Serum microRNA-221 as a biomarker for diabetic retinopathy in patients associated with type 2 diabetes》

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BMI:Body mass index；BUN:Blood urea nitrogen；DBP:Diastolic blood pressure；FPG:Fasting plasma glucose；HbA1c:Glycated hemoglobin；HC:Healthy control；HDL-C:High-density lipoprotein cholesterol；HOMA-IR:Homeostatic model assessment of insulin resistance；LDL-C:Lo

Baseline Characteristics No significant differences were found in age，gender，body mass index，diastolic blood pressure，systolic blood pressure，total cholesterol，triglyceride，high-density lipoprotein，low-density lipoprotein，serum creatinine and blood urea nitrogen among these four groups（P>0.05）.However，diabetes duration，fasting blood glucose（FBG），glycated hemoglobin（HbA1c）and homeostasis model assessment for insulin resistance（HOMA-IR）in patients with T2D were increased significantly compared to HC group（P<0.001）.Additionally，of patients with T2D，diabetes duration，HbA1c and HOMA-IR in PDR and NPDR group were increased significantly compared to NDR group（P<0.05）.Furthermore，diabetes duration and HbA1c in PDR group were increased significantly compared to NPDR group（P<0.05）.Baseline characteristics of the recruited subjects are listed in Table 1.