《Table 3–Influence on entrapment efficiency and drug loading of different ratio of the SA:drug.》

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《Two kinds of ketoprofen enteric gel beads(CA and CS-SA) using biopolymer alginate》

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As shown in Table 1，we could see that with the increase of molecular weight of sodium alginate，the drug loading and entrapment efficiency of CS-SA gel beads increased significantly.As the concentration of sodium alginate used in the preparation was relatively low，the molecular weight of sodium alginate played an important role in the viscosity of the solution，the higher the molecular weight of sodium alginate，the greater the viscosity of the solution，which lead to better drug suspension and less drug leakage in the process of forming film.Moreover，the G/M value of polymer sodium alginate used in the experiments was relative high，so it was easy to form three dimensional network structure with Ca2+，leading to the decrease of film forming time.