《Table 1 Ongoing trials on lung cancer immunotherapy》

《Table 1 Ongoing trials on lung cancer immunotherapy》   提示:宽带有限、当前游客访问压缩模式
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《Immunotherapy–new perspective in lung cancer》


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1ClinicalTrials.gov registry number.NSCLC:Non-small cell lung cancer.

Durvalumab was compared to placebo in stage III NSCLC patients after unsuccessful chemoradiotherapy.The 24-mo OS rate was better in the immunotherapy group(66.3%vs 55.6%).The median time to death or distant metastasis was 28.3 mo vs 16.2mo also better in the durvalumab group.The most frequent AE leading to the discontinuation of treatment was pneumonitis(4.8%in durvalumab group vs 2.6%in placebo group).Death due to AEs occurred in durvalumab(4.4%)and placebo group(6.4%)[34].After that trial,the idea of immunotherapy for adjuvant setting was rekindled,and,nowadays,have been evaluated by an amount of current studies[35](Table 1).