《Tab.3 Comparison of data of our study and three previous studies》

《Tab.3 Comparison of data of our study and three previous studies》   提示:宽带有限、当前游客访问压缩模式
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《CD40-1C/T基因多态性与中国汉族人群脑卒中遗传易感性的研究(英文)》


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By using the combined keywords“CD40”,“polymorphism”,“stroke”,“association”searching in the PubMed database dating up to 21 October 2017,we found 7studies evaluating the association between polymorphisms of CD40and stroke.After further scrutinize for studies focusing on stroke in which SNPs examined overlapped with ours,only 3studies were finally recruited in the meta-analysis.These studies all focused on IS,as a result,our meta-analysis only considered the association between IS and CD40-1C>T.The comparison of our study and previous studies were shown in Tab.3.Forests plot for rs1883832from 4studies including our own were shown in Fig.1.There was a significant association between rs1883832and IS(P<0.00001,OR=1.39[95%CI=1.25-1.56])yielding 1.39per T allele copy,with no evidence for statistical heterogeneity(P=0.74,I2=0%)between studies.This meta-analysis indicated that the T allele was associated with increased risk of IS,which was consistent with our study.