《Table 3 Quality assessment of included case-control studies according to NHBLI Quality Assessment T

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《"Spontaneous fungal peritonitis: Micro-organisms, management and mortality in liver cirrhosis-A systematic review"》

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In conclusion，SFP is not an uncommon complication in cirrhotic patients and associated with high mortality both in the hospital and at 1 mo.High clinical suspicion is required particularly in those with higher MELD and Child Pugh scores who fail to improve despite appropriate antibiotic treatment.Antifungal therapy is inappropriately used and currently underutilized.Our review suggests rapid initiation of antifungal therapy in the presence of septic shock and failure to respond to broad spectrum antibiotic regimen.It also highlights the need for further studies that will inform the timing and choice of anti-fungal use in patients at high-risk for SFP.Finally，our review also shows that liver transplantation is a possible outcome for those with SFP with low risk for short-term recurrence and acceptable 1-mo mortality rates.