《Table 4 Multivariable analysis of risk factors for development of a major bleed in patients with he

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《Effectiveness of venous thromboembolism prophylaxis in patients with liver disease》

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While the incidence of VTE has been well established in patients with cirrhosis，whether pharmacological VTE prophylaxis should be provided in an attempt to decrease this incidence is not well known.Major VTE prophylaxis guidelines are silent on this topic[23].Therefore，this study was conducted to evaluate whether patients with cirrhosis experienced net benefit or harm when prophylactic anticoagulation was provided.We found that those who received pharmacological prophylaxis experienced the primary outcome of incident VTE or incident major bleeding less frequently，although this difference was driven by decreased rates of major bleeding（Table 2）.