《Table 2 Characteristics of included studies:Vitamin D treatment and evaluating bone health in child

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《Vitamin D therapy in children with inflammatory bowel disease: A systematic review》

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1Number of patients recruited（type of disease）；2Serum levels expressed as mean±SD，mean and interquartile range，or mean；3Disease activity scores（Pediatric Crohn disease activity index or Pediatric ulcerative colitis disease activity index）at baseline

Five studies were designed to investigate the effect of vitamin D therapy on increasing vitamin D levels（Table 1），and four were designed to investigate the effect of therapies on parameters of bone health（Table 2）.The final study was designed to investigate vitamin D therapy for maintaining sufficient vitamin D levels[21].In the studies concerning bone health，vitamin D therapy was not the main intervention given；in one study vitamin D was administered to both the intervention and placebo group.