《Table 1 Characteristics of the studies included in the meta-analysis》
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《High-risk symptoms and quantitative faecal immunochemical test accuracy: Systematic review and meta-analysis》
1Age is expressed as median;AbPa:Abdominal pain;AD:Antithrombotic discontinuity;An:Anaemia;AN:advanced neoplasia;AnS:Any symptom;AU:Australia;CN:China;Co:Constipation;CRC:Colorectal cancer;ChBo:Change in bowel habit;DC:Derivation cohort;Di:Diarrhoea;ES:Sp
We found substantial heterogeneity between studies when calculating the pooled sensitivity for almost every threshold analysed in the studies evaluating OC-Sensor?(Table 3).Spearman’s rank correlation coefficient was higher than 0.1,suggesting an absence of threshold effect in all cases.The scarce number of studies limited our intent to determine the existence of publication bias using funnel plots.However,when plotting each study’s diagnostic odds ratio(dOR)in a logarithmic scale against its sample size,we did not identify any trends towards asymmetry around the axis traced by the pooled dOR value for any analysed threshold,which suggests the absence of this possibility(Figure 5).
图表编号 | XD0064288200 严禁用于非法目的 |
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绘制时间 | 2019.05.21 |
作者 | Noel Pin Vieito、Sara Zarraquios、Joaquín Cubiella |
绘制单位 | Department of Gastroenterology, Complexo Hospitalario Universitario de Ourense、Instituto de Investigación Sanitaria Galicia Sur、Department of Biochemistry, Genetics and Immunology, Faculty of Biology University of Vigo、Department of Gastroenterology, Comp |
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