《Table 3 Maspin expression in brain, organs of the head and neck area, skin and soft tissues》

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《Subcellular expression of maspin – from normal tissue to tumor cells》

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SCC:Squamous cell carcinoma.

Ovary:Expression of maspin was not present in the normal ovary[27-30].In ovarian carcinomas，maspin expression in over 50%of the tumor cells was associated with higher tumor grade，positive peritoneal effusion cytology，lower survival rate，and positivity for the proangiogenic factors VEGF-A，-C，and-D[27，28].Most of the malignant tumors presented with cytoplasmic only expression，but those with low malignant potential showed mixed positivity（cytoplasm and nucleus）[29].The localization of maspin expression might have therapeutic importance because the cytoplasmic positivity associates with cisplatin sensitivity[30]（Table 1）.