《Table 1 Axons and foot ulcers in the aligned and random nanofiber NGC groups》

《Table 1 Axons and foot ulcers in the aligned and random nanofiber NGC groups》   提示:宽带有限、当前游客访问压缩模式
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《Aligned fibers enhance nerve guide conduits when bridging peripheral nerve defects focused on early repair stage》


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P-values are based on Fisher’s method on 2×2 cross tabulation(Fisher’s exact test).NGC:Nerve guide conduit;NF200:neurofilament.

No bridging matrix was formed at 21 or 35 days.We selected the regenerative matrix that formed at 49 days for further analyses(Figure 7).Given that several studies have indicated that it is difficult to accurately measure the length of axonal outgrowth,the presence of axons was used to assess axonal outgrowth(Meyer et al.,2016;Stenberg et al.,2016).Axons were observed in the middle of the formed matrices in 6/7(85%)of the random nanofiber nerve guide conduits and in 7/7(100%)of the aligned nanofiber nerve guide conduits.In the distal nerve segment,neurofilament-positive staining was detected in 4/7(57%)of the random nanofiber nerve guide conduits and in 7/7(100%)of the aligned nanofiber nerve guide conduits.Chi-square tests showed a statistically significant difference in the presence of new neurofilaments in the distal nerve segment between the aligned and random nanofiber nerve guide conduits;however,there were no differences in the middle segment.In addition,there were no differences in the number of foot ulcers(Table1 and Figure 7).