《Table 1 Correlation of tau protein levels (pg/mL) in cerebrospinal fluid and serum in SCI rats (Pea

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《Serum and cerebrospinal fluid tau protein level as biomarkers for evaluating acute spinal cord injury severity and motor function outcome》

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The data are analyzed from the four groups（sham group，mild SCIgroup，moderate SCI group and severe SCI group，n=20）.SCI:Spinal cord injury.

As shown in Figure 1，the tau protein level in serum and CSF was slightly increased in the sham group at 12 hours after SCI compared with 1 hour after SCI.However，there was no significant difference in comparison with the rest of the time points.In all SCI rats，the levels of serum and CSF tau protein were increased at 1 hour to 6 hours after SCI，reached a peak at 12 hours，and then slowly decreased.However，tau protein levels in serum and CSF were relatively high for a period both in the moderate and severe SCI groups.Significant correlations were detected between CSF tau protein levels and serum tau levels at each time point in SCI rats（Table 1）.