《Table 3Multivariate analysis to determine the independent contributors to the development of ER in

  提示：宽带有限、当前游客访问压缩模式

本系列图表出处文件名：随高清版一同展现

《Preoperative risk factors for early recurrence in patients with resectable pancreatic ductal adenocarcinoma after curative intent surgical resection》

1. 获取 高清版本忘记账户？点击这里登录

1. 下载图表忘记账户？点击这里登录

ER:early recurrence；PDAC:pancreatic ductal adenocarcinoma；CRP:C-reactive protein；SUVmax:maximum standardized uptake value；PET-CT:positron emission tomography-computed tomography.

ER occurred in 26 patients（32.1%）.Among non-ER patients，49（60.5%）had late recurrence，6（7.4%）had no recurrence.The incidence of liver metastasis was significantly higher in the ER group than in the non-ER group（53.8%versus 10.4%，P<0.01）.The incidence of local recurrence（23.1%versus 39.6%）and distant metastasis（23.0%versus 50.0%）were lower in the ER group compared to that in the non-ER group.Univariate analysis using only preoperative variables was done to predict ER in patients with R-PDAC.Results showed that operative time≥500 min，CRP>3.0 mg/dL，m GPS score=2，decrease of total lymphocyte count>50%of baseline value，PNI<45，neutrophil-to-lymphocyte ratio（NLR）≥3，and preoperative SUVmax were significantly associated with the occurrence of ER in patients with R-PDAC（Table 1）.Univariate analysis using immediate postoperative variables showed UICC stage，pT stage and pathological grade were significantly associated with the occurrence of ER in patients with R-PDAC（Table 2）.Distribution of patients receiving adjuvant chemotherapy was not significantly different between ER group and non-ER group（84.6%versus 74.5%，P=0.397，Table 2）.Among the preoperative factors，a multivariate logistic regression analysis with forward stepwise conditional method revealed that CRP>3.0 mg/dL，decrease of total lymphocyte count>50%of baseline，and preoperative SUVmax were significant and independent contributors to the occurrence of ER in patients with R-PDAC（Table 3）.Overall，the 1-，2-，3-，and 5-year survival rates in the non-ER group and ER group were 90.2%，67.7%，49.9%，and 13.2%，versus 37.9%，0%，0%，and 0%，respectively（P<0.01，Fig.1）.And non-ER group had longer median survival time than ER group（23 months versus 10 months，Fig.1）.