《Table 2Effect of PAME on biochemical parameters in vincristine induced neuropathic pain in rats.》

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《NO-cGMP-K channel-dependent anti-nociceptive activities of methanol stem bark extract of Piptadeniastrum africanum(Mimosaceae) on rats》

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Each value represents the mean±ESM for 6 animals and analysed by two-way ANOVA followed by Tukey post-hoc test，α毩P<0.05；毬P<0.01；毭P<0.001statistically significant compared to normal control.bP<0.01，cP<0.001 statistically significant compared to vincr

The significant increase（P<0.001）in levels of platelets，white blood cell（WBC）and the significant decrease in levels of red blood cell（RBC）（P<0.01） ，haemoglobin（Hb）（P<0.001） and hematocrit（P<0.05）were observed in untreated group.However，the treatment with PAME（500 mg/kg）and morphine（5 mg/kg）revealed an significant increase in Hb（P<0.05），RBC（P<0.05）and hematocrit（P<0.05）.In a similar way，the PAME（500 mg/kg）significantly reduced the increase of platelets（P<0.001）and WBC（P<0.01）and finally，their results were very close to those of animals of the normal control group（Table 1）.