《遗传学》

Section A-Molecular genetics1

A1　DNA structure1

A2 Genes6

Preface8

A3　The genetic code10

A4Gene transcription13

A5　Transfer RNA21

A6 Ribosomal RNA25

A7 Messenger RNA29

A8 Translation35

A9　DNA replication43

A10　Regulation of gene expression in prokaryotes49

A11　Regulation of gene expression in eukaryotes56

B1 Chromosomes63

Section B-Genomes63

B2Cell division72

B3　Prokaryotic genomes75

B4　The human genome　80

B5　DNA mutation86

B6 Mutagens and DNA repair92

B7 Recombination99

B8 Bacteriophages106

B9 Eukaryotic viruses112

Section C-Mechanisms of inheritance119

C1Basic Mendelian genetics119

C2 More Mendelian genetics126

C3 Meiosis and gametogenesis134

C4　Linkage141

C5　Transfer of genes between bacteria148

C6 Genes in eukaryotic organelles155

C7 Quantitative inheritance159

C8 Sex determination169

C9 Sex and inheritance174

C10 Somatic cell fusion177

C11 Inbreeding183

C12　Probabilities188

C13　Tests for goodness of fit: chi-square and exact tests193

Section D-Population genetics and evolution199

D1Introduction199

D2 Evolution by natural selection203

D3 Genes in populations: Hardy-Weinberg equilibrium210

D4 Genetic diversity218

D5 Neo-Darwinian evolution selection acting on alleles223

D6 Chromosome changes in evolution228

D7 Species and speciation239

D8 Polyploidy246

D9 Evolution251

Section E-Recombinant DNA technology259

E1Nucleic acid hybridization259

E2 DNA cloning264

E3 Polymerase chain reaction(PCR)274

E4 DNA sequencing278

Section F-Applications of genetics283

F1Genetic diseases283

F2 Genes and cancer293

F3 Genotoxicity testing298

F4 Gene therapy302

F5 The human genome project306

F6 Genetics in forensic science313

F7 Genetic engineering and blotechnology321

Further reading331

Index335