《Table 2 Top-three GO terms with highest fold enrichment scores of differentially expressed genes wi
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《Bioinformatics analyses of differentially expressed genes associated with spinal cord injury:a microarray-based analysis in a mouse model》
P<0.05,sorted by fold enrichment score.GO:Gene Ontology;STAT:signal transducer and activator of transcription.
The gene expression dataset,GSE5296,was used to identify DEGs from a SCI murine model using a microarray representing approximately 34,000 genes.By comparing the control group and SCI subgroups at each time point,several DEGs were identified,with the numbers shown in Figure1.SCI led to upregulation of 2,460 genes in injured spinal cord at 7 days after injury,109 of which were upregulated at each time point.Moreover,many of these upregulated genes were associated with inflammation.In total,2010 genes were downregulated at the injury site at 7 days following SCI,30 of which were downregulated at each time point.Interestingly,the number of downregulated genes was always smaller than the number of upregulated genes at each time point.Overall,we identified 109 upregulated genes and 30downregulated genes with consistent directions of variation at each time point(Figure 2).Additional Table 1 contains the complete list of DEGs.
图表编号 | XD0040618900 严禁用于非法目的 |
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绘制时间 | 2019.07.01 |
作者 | Lei Guo、Jing Lv、Yun-Fei Huang、Ding-Jun Hao、Ji-Jun Liu |
绘制单位 | Department of Spinal Surgery,Honghui Hospital,Xi'an Jiaotong University、Department of Clinical Laboratory,Honghui Hospital,Xi'an Jiaotong University、Department of Spinal Surgery,Honghui Hospital,Xi'an Jiaotong University、Department of Spinal Surgery,Ho |
更多格式 | 高清、无水印(增值服务) |
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