《Table 1.The system for screening NDM-1 inhibitors.》

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《IMB-XH1作为新型新德里金属-β-内酰胺酶-1(NDM-1)抑制剂的研究（英文）》

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The volume of the screening system was 200μL；+:the component was added into the screening system；–:the component was not added into the screening system.

The screening system is shown in Table 1 and performed in 96-well UV plates.The Z’-factor，signal to background ratio（S/B），signal to noise ratio（S/N）and coefficient of variation（CV）of the screening model were evaluated to fit for the high throughput screening（Table 2）.Especially，IMB-XH1 as an NDM-1 inhibitor at the concentration of 20μg/mL was selected out from 52 100 compound samples，and its IC50 value is 0.4637μM.The chemical formula and molar mass of IMB-XH1 is C18H14N3OS and 333.4149 g/mol，respectively（Fig.4）.