《T a b l\n\t\t\t\t\t\te2Mi c r o RNAs i n h u m a n p a t i e n t s w i t h Al z h e i m e r’
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《MicroRNAs as diagnostic and therapeutic tools for Alzheimer's disease: advances and limitations》
M MSE:Mi n i-Me n t a l\n\t\t\t\t\t\tSt a t e Ex a m i\n\t\t\t\t\t\tn a t i\n\t\t\t\t\t\to n;Mo CA:Mo n\n\t\t\t\t\t\tt r e a\n\t\t\t\t\t\tl Co g\n\t\t\t\t\t\tn i t i v e As s e s s m e n t.
By qPCR validation,Ren et al.(2016)showed miR-339 and miR-425 were upregulated and miR-639 was downregulated in AD PBMNs compared with NC PBMNs.ROC indicated miR-339 as a fair test to distinguish AD PBMNs from NC PBMNs(AUC 0.768),and miR-425 to be a good test to distinguish AD PBMNs from NC PBMNs(AUC 0.868).MiR-639was a poor test to distinguish AD PBMNs from NC PBMNs(AUC 0.287).Theβ-amyloid precursor proteinβ-secretase BACE1 might be a target of miR-339 and miR-425.
图表编号 | XD0040608100 严禁用于非法目的 |
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绘制时间 | 2019.02.01 |
作者 | Bridget Martinez、Philip V.Peplow |
绘制单位 | Department of Physics and Engineering, Los Alamos National Laboratory、Department of Anatomy, University of Otago |
更多格式 | 高清、无水印(增值服务) |
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