《the renal origin of hypertension P127》求取 ⇩

INTRODUCTION3

Production of Experimental Renal Hypertension by Various Methods6

Unilateral and bilateral nephrectomy6

Reduction of the amount of functioning renal tissue6

The effect of a nephrotic substance7

Irradiation with roentgen rays7

Occlusion of one or both ureters7

Compression of the kidneys8

Embolism8

Passive hyperemia8

Permanent occlusion of the main renal artery，vein，and ureter8

Arteriovenous anastomosis9

Occlusion of the main renal arteries9

Ligation of branches of the main renal artery9

Constriction of the main renal artery9

The administration of sterols9

PRODUCTION OF EXPERIMENTAL RENAL HYPERTENSION BY CONSTRICTION OF MAIN RENAL ARTERY12

EFFECT ON BLOOD PRESSURE OF MODERATE CONSTRICTION OF THE MAIN ARTERY OF ONLY ONE KIDNEY15

EFFECT ON BLOOD PRESSURE OF MODERATE CONSTRICTION OF BOTH MAIN RENAL ARTERIES：THE BENIGN PHASE OF EXPERIMENTAL RENAL HYPERTENSION18

EFFECT ON BLOOD PRESSURE OF GREAT CONSTRICTION OF BOTH MAIN RENAL ARTERIES：THE MALIGNANT PHASE OF EXPERIMENTAL RENAL HYPERTENSION27

PATHOLOGIC CHANGES IN THE ORGANS OF ANIMALS WITH PERSISTENT HYPERTENSION29

Pathogenesis of arteriolar necrosis32

Other changes in experimental renal hypertension32

PATHOGENESIS(MECHANISM OF DEVELOPMENT) OF EXPERIMENTAL RENAL HYPERTENSION37

Neurogenic mechanism39

Endocrinogenic mechanism40

THE HUMORAL MECHANISM OF EXPERIMENTAL RENAL HYPERTENSION51

RENAL ORIGIN OF HYPERTENSION54

RENIN61

Chemical properties61

Physiological properties62

Fate of renin in the body67

Methods for the assay of renin：the unit of renin69

HYPERTENSINOGEN70

Nature and properties70

Unit of hypertensinogen71

Preparation72

Hypertensin73

Chemical properties73

Preparation and purification75

Physiological properties76

Unit of hypertensin79

HYPERTENSINASE80

Nature and properties80

The unit of hypertensinase81

The amount of hypertensinase in the blood and various organs81

Mechanism of action of hypertensinase82

MECHANISM AND SITE OF FORMATION AND RELEASE OF RENIN84

THE JUXTAGLOMERULAR APPARATUS88

THE TREATMENT OF HYPERTENSION90

Medical Treatment90

Extracts of kidney92

Antirenin：treatment of hypertension by the parenteral injection of renin96

Other vasoconstrictor，pressor and antipressor substances，and their effects101

Surgical Treatment109

Unilateral nephrectomy for hypertension due to unilateral renal disease110

SUMMARY OF THE SIMILARITIES AND DIFFERENCES BETWEEN HUMAN ESSENTIAL AND EXPERIMENTAL HUMAN HYPERTENSION114